--- title: "JoVE x BrRN: A Shared Mission for Science Reproducibility" description: Discover how JoVE and the Brazilian Reproducibility Network (BrRN) partner to advance transparent, reliable, and reproducible science. image: https://blog.jove.com/hubfs/BRN%20Reproducibility%20blog%20post_final.png --- [JoVE](https://www.jove.com/) [Faculty Resource Center](https://app.jove.com/playlist/library/all) Research![](https://blog.jove.com/hubfs/raw_assets/public/Blog-design-template-2022/Jove_july2k22_test/template/icons/chevron-down-regular.svg) [Behavior](https://www.jove.com/research/behavior) [Biochemistry](https://www.jove.com/research/biochemistry) [Bioengineering](https://www.jove.com/research/bioengineering) [Biology](https://www.jove.com/research/biology) [Cancer Research](https://www.jove.com/research/cancer-research) [Chemistry](https://www.jove.com/research/chemistry) [Developmental Biology](https://www.jove.com/research/developmental-biology) 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Feedback](https://www.jove.com/about/contact) [About Us](https://www.jove.com/about/) [← Previous Page](https://blog.jove.com) [← Previous Page](https://blog.jove.com) ![](https://blog.jove.com/hubfs/BRN%20Reproducibility%20blog%20post_final.png) ![...](https://blog.jove.com/hubfs/BRN%20Reproducibility%20blog%20post_final.png) Librarian research # JoVE x BrRN: A Shared Mission for Science Reproducibility Ellen Ovenden, MSc | Sep 04, 2025 [![](https://cloudfront.jove.com/img/icons/linkedin-in-brands_white.svg)](https://www.linkedin.com/shareArticle?mini=true&url=https://blog.jove.com/brrn-reproducibility-2025) [![](https://blog.jove.com/hubfs/Imported%20images/twitter-white.png)](http://www.twitter.com/share?url=https://blog.jove.com/brrn-reproducibility-2025) [![](https://cloudfront.jove.com/img/icons/facebook-square-brands_white.svg)](https://www.facebook.com/sharer/sharer.php?u=https://blog.jove.com/brrn-reproducibility-2025) Ellen Ovenden, MSc | Sep 04 2025 [![](https://cloudfront.jove.com/img/icons/linkedin-in-brands_white.svg)](https://www.linkedin.com/shareArticle?mini=true&url=https://blog.jove.com/brrn-reproducibility-2025) [![](https://blog.jove.com/hubfs/Imported%20images/twitter-white.png)](http://www.twitter.com/share?url=https://blog.jove.com/brrn-reproducibility-2025) [![](https://cloudfront.jove.com/img/icons/facebook-square-brands_white.svg)](https://www.facebook.com/sharer/sharer.php?u=https://blog.jove.com/brrn-reproducibility-2025) When Dr Jan Lötvall’s lab published their game-changing RNA isolation method, the University of Gothenburg researchers faced a new challenge: a high volume of queries from scientists trying to run the complex new protocol in their own labs. By [**creating a video with JoVE**](https://app.jove.com/v/3037/isolation-and-characterization-of-rna-containing-exosomes), the authors enabled others to visualize every intricate detail of the experiment. Today, their video article has **almost 100,000 views** and **over 600 citations**. Reproducibility is the foundation of trustworthy science. Yet many researchers face difficulties replicating experiments described in traditional articles, where important details are sometimes left out. That challenge is at the heart of both JoVE’s and the [**Brazilian Reproducibility Network**](https://www.reprodutibilidade.org/)’s (**BrRN**) efforts. JoVE bridges the gap between written descriptions and practical execution with peer-reviewed video articles that make methods clearer and more reproducible. BrRN addresses the same challenge within Brazil’s research community and beyond.  We are **proud to introduce BrRN as a new collaborator** and to share their work with the JoVE community. Let’s learn a little more about them. --- ### What is BrRN? Founded in 2023, BrRN is a national initiative to make science in Brazil more reliable and transparent. It connects researchers, institutions, and policymakers around a shared goal: embedding rigorous and collaborative practices into everyday research.  Aligning with Brazil’s **broader commitments to open science**,1 BrRN supports the adoption of reproducible practices through **training, resources, and advocacy** at institutional and governmental levels.  Specifically, BrRN’s current activities include adapting the UK Reproducibility Network’s [**reproducibility “primers”**](https://www.ukrn.org/primers/) for the Brazilian context, preparing an [**open online course on reproducible science**](https://www.reprodutibilidade.org/projetos) (expected to launch in 2026), and engaging with [**international networks**](https://www.ukrn.org/global-networks/) to strengthen training and development across the Global South. --- ### Why BrRN Matters A large multicenter project in Brazil recently attempted to **replicate a set of 56 biomedical experiments** carried out in local labs.2[**Fewer than half of the studies**](https://www.reprodutibilidade.org/en/post/the-first-results-of-the-brazilian-reproducibility-initiative-are-now-published-in-preprint-format) reproduced the original results, highlighting how communication gaps and inconsistent reporting can undermine research credibility. For example, small differences in how cell cultures were handled or how reagents were prepared often explained why replication failed.  These findings show that reproducibility issues are not just theoretical; they directly affect the credibility of published results and the efficiency of research investments. This context makes the work of the Brazilian Reproducibility Network (BrRN) especially urgent. --- ### Why Video Matters - [![BrRN gif 1](https://blog.jove.com/hs-fs/hubfs/BrRN%20gif%201.gif?width=800&height=432&name=BrRN%20gif%201.gif)](https://app.jove.com/science-education/v/14435/combined-effects-of-drugs-synergism) - [![BrRN gif 2](https://blog.jove.com/hs-fs/hubfs/BrRN%20gif%202.gif?width=800&height=432&name=BrRN%20gif%202.gif)](https://app.jove.com/science-education/v/15092/first-order-circuits) - [![JoVE gif 6 (1)](https://blog.jove.com/hs-fs/hubfs/JoVE%20gif%206%20(1).gif?width=995&height=537&name=JoVE%20gif%206%20(1).gif)](https://app.jove.com/science-education/v/11291/hess-s-law-of-constant-heat-summation) As BrRN works to strengthen research culture in Brazil and beyond, **JoVE adds a practical piece to the puzzle: video**. This helps overcome one of the biggest barriers to reproducibility, namely the limitations of text. Reproducibility often fails because written methods cannot capture every detail. A slight nuance in technique, the way equipment is positioned, or the pace of adding a reagent can mean the [**difference between success and failure**](https://blog.jove.com/research-silent-saboteurs?hsLang=en).  “Sometimes you’re reading directions, and the words just don’t make sense,” says Jeanette Moore, researcher and lab manager at the University of Alaska Fairbanks. “That is the value of JoVE, actually seeing how to insert a needle in a laboratory animal before you do it, so you don’t have to do it twice.”  When experienced researchers leave a lab, their skills often disappear with them. Videos can act as a long-term archive. Recording methods ensures that **knowledge is preserved** and [**available to the next generation of scientists**](https://cdn.mediavalet.com/usva/jove/9mBUzfkty02K4jrLyGk65Q/kKewqoJjikmo-eCM1N522w/Original/Alaska_ResearchCaseStudy_2025.pdf). Institutions that integrate JoVE into their lab training report [**accelerated learning**](https://cdn.mediavalet.com/usva/jove/p8ao_isByEyKyc_VE4-itA/FsqMNIHRUUSY5WV48b_bug/Original/JoVE%20Stanford%20Case%20Study.pdf) and [**reduced costs**](https://cdn.mediavalet.com/usva/jove/5FJHGUjtjkqmsITt_NM12Q/Kyk1pEOYj0O7l2ZknIy1uw/Original/Biogen%20Research%20Case%20Study.pdf). By standardizing training, researchers across institutions and countries are able to start off with the **same foundation in reproducible methods**, leveling the playing field for those in resource-constrained environments. --- ### The JoVE x BrRN collaboration As part of a shared commitment to reproducibility, JoVE has partnered with BrRN to strengthen reliable science in Brazil. The pilot phase of the collaboration includes: - ◽ **Six-month access** to JoVE video resources for **60 members** of BrRN’s immediate network - ◽ **Webinars and training sessions** to demonstrate how video-based methods strengthen reproducibility Additionally, several major Brazilian universities, including **University of São Paulo (USP)**, **University of Campinas (UNICAMP)**, **Rio de Janeiro State University (UERJ)**, and **Goiás State University (UEG)**, already have JoVE access, giving many local researchers a direct path to these resources. --- ### Key Takeaways The story of Dr. Lötvall’s lab shows how powerful video can be in turning a promising discovery into a widely applied method.  Irreproducible findings can have a far-reaching ripple effect in science, affecting future research studies and scientific decision-making. JoVE was founded with reproducibility at its core. By pairing text with video, it addresses a fundamental gap in scientific communication. But **making research more reliable also requires cultural and structural change**. BrRN is helping Brazil take this step by building research communities, expanding training, and advocating for transparent, accessible, and reproducible research.  Together, **JoVE and BrRN are advancing reproducibility in Brazil** and providing an example of how institutions and researchers worldwide can strengthen reliable, transparent science. ### Building reproducibility starts with the right tools. **Learn how JoVE videos support reproducible and productive research.** [Start your trial](https://info.jove.com/blog-brrn-research-trialrequest?hsLang=en) 1. Collaborative practices for science and technology (BR0125). In *Brazil action plan 2023–2027 (December)*. [https://www.opengovpartnership.org/members/brazil/commitments/BR0125/](https://www.opengovpartnership.org/members/brazil/commitments/BR0125/?utm_source=chatgpt.com) 2. Brazilian Reproducibility Initiative. (2025, April 25). Estimating the replicability of Brazilian biomedical science (preprint). *bioRxiv*. 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