JoVE BLOG | JoVE

Inside AstraZeneca: 4 Practical Lessons for 3Rs Implementation

Written by Ellen Ovenden | Aug 30, 2026, 4:12:11 PM

At AstraZeneca, one 3Rs initiative went from an idea in 2018 to global standard practice across animal research in 2020.

In the JoVE webinar Identifying and Implementing the 3Rs in Preclinical Research: Examples and Outcomes, Dr Krystal Nacel, Associate Director at AstraZeneca, describes the 3Rs as "improving animal welfare, strengthening study design, and supporting better science.”

Let's explore four lessons from the webinar on how to put these principles into practice, including where visual training materials can help.