--- title: "Cutting-edge Research: JoVE partners with US Government" description: "Cutting-edge Research: JoVE partners with US Government" image: https://blog.jove.com/hubfs/JoVE%20in%20Action%20banner%20(1140%20%C3%97%20415%20px)%20(1800%20%C3%97%20900px)%20(7).png --- [JoVE](https://www.jove.com/) [Faculty Resource Center](https://app.jove.com/playlist/library/all) Research![](https://blog.jove.com/hubfs/raw_assets/public/Blog-design-template-2022/Jove_july2k22_test/template/icons/chevron-down-regular.svg) [Behavior](https://www.jove.com/research/behavior) [Biochemistry](https://www.jove.com/research/biochemistry) [Bioengineering](https://www.jove.com/research/bioengineering) [Biology](https://www.jove.com/research/biology) [Cancer Research](https://www.jove.com/research/cancer-research) [Chemistry](https://www.jove.com/research/chemistry) [Developmental Biology](https://www.jove.com/research/developmental-biology) [Engineering](https://www.jove.com/research/engineering) 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Us](https://www.jove.com/about/) [← Previous Page](https://blog.jove.com) [← Previous Page](https://blog.jove.com) ![](https://blog.jove.com/hubfs/JoVE%20in%20Action%20banner%20(1140%20%C3%97%20415%20px)%20(1800%20%C3%97%20900px)%20(7).png) ![...](https://blog.jove.com/hubfs/JoVE%20in%20Action%20banner%20(1140%20%C3%97%20415%20px)%20(1800%20%C3%97%20900px)%20(7).png) Researchers # Cutting-edge Research: JoVE partners with US Government Neal Moawed, JoVE Writer | May 15, 2012 [![](https://cloudfront.jove.com/img/icons/linkedin-in-brands_white.svg)](https://www.linkedin.com/shareArticle?mini=true&url=https://blog.jove.com/librarian-blog/cutting-edge-research-jove-partners-with-us-government) [![](https://blog.jove.com/hubfs/Imported%20images/twitter-white.png)](http://www.twitter.com/share?url=https://blog.jove.com/librarian-blog/cutting-edge-research-jove-partners-with-us-government) [![](https://cloudfront.jove.com/img/icons/facebook-square-brands_white.svg)](https://www.facebook.com/sharer/sharer.php?u=https://blog.jove.com/librarian-blog/cutting-edge-research-jove-partners-with-us-government) Neal Moawed, JoVE Writer | May 15 2012 [![](https://cloudfront.jove.com/img/icons/linkedin-in-brands_white.svg)](https://www.linkedin.com/shareArticle?mini=true&url=https://blog.jove.com/librarian-blog/cutting-edge-research-jove-partners-with-us-government) [![](https://blog.jove.com/hubfs/Imported%20images/twitter-white.png)](http://www.twitter.com/share?url=https://blog.jove.com/librarian-blog/cutting-edge-research-jove-partners-with-us-government) [![](https://cloudfront.jove.com/img/icons/facebook-square-brands_white.svg)](https://www.facebook.com/sharer/sharer.php?u=https://blog.jove.com/librarian-blog/cutting-edge-research-jove-partners-with-us-government) Today marks an important day in *JoVE's* history. Today *JoVE, The Journal of Visualized Experiments,* published two articles in partnership with the United States government's Defense Threat Reduction Agency (DTRA). *JoVE* is proud to present the work from Temple University's Dr. Chris Schafmeister and State University of New York Buffalo's Dr. David Pawlowski and Dr. Richard Karalus. The support of scientists conducting research for DTRA has significant ramifications for identifying, treating, and preventing the outbreak of defense threats. DTRA exists to safeguard America and its allies from weapons of mass destruction (WMD), including chemical, biological, radiological, nuclear weapons and high-yield explosives (CBRNE), by providing capabilities to reduce, eliminate, and counter the threat and mitigate its effects. Because the techniques and technologies developed in DTRA sponsored laboratories promise a safer world and will benefit from distribution in a highly visual format, DTRA has sponsored the research and publication of their scientists in *JoVE.* From Temple University, award winning scientist Dr. Chris Schafmeister, working with Conrad Pfeiffer, developed a biochemical technique that produces new, complex polymers called bis-peptides. So what is a bis-peptide? Dr. Schafmeister explains, "We were synthesizing a 'three-mer,' a molecule with three parts, and Conrad was taking you through the process of preparing the resin, building the building block on it, verifying that it's there, and then removing the protecting group, and then removing the three-mer from the resin itself." He goes on, "The building blocks and the final molecule are special. Our molecules bind with two bonds to each molecule, unlike the typical single bond, making a stiff, ladder-like construct." Dr. Schafmeister won the "Outstanding Scientific Achievement Award" from the Chemical and Biological Defense Science and Technology conference for his work. Dr. Schafmeister, choosing to publish his research in *JoVE*, notes, "This procedure demonstrates cutting edge capabilities that don't exist anywhere else. Hopefully, they will lead to products in the next decade far beyond anything we can produce right now." Find Dr. Schafmeister and Mr. Pfeiffer's work [here](http://www.jove.com/video/4112/solid-phase-synthesis-of-a-functionalized-bis-peptide-using-safety-catch-methodology). In the second DTRA sponsored *JoVE* article, Dr. David Pawlowski and his colleague Dr. Richard Karalus publish their procedure on the isolation of nucleic acids and proteins, *without* electricity or laboratory support. This work has significant implications for real time threat monitoring. Dr. Pawlowski explains, "This is a handheld electricity-free device which can be used in the field by the warfighter, in conjunction with their detection platforms." He continues, stating that this technique will "be useful for detection of typical biological warfare agents." The research is particularly exciting as "This is the first example that we know of a method to isolate nucleic acids followed by proteins in a sequential manner from a sample, without having to split the sample." Dr. Pawlowski notes that he and his colleagues were incredibly satisfied with their experience publishing in this format. "My reason for publishing this in *JoVE* is that *a video article* offered us the opportunity to provide a visualization of this small, handheld tool. Giving a simple, verbal description is difficult, so a *JoVE* publication helps with training the warfighters how to use the technique." Find Dr. Pawlowski and Dr. Karalus' work [here.](http://www.jove.com/video/4202/electricity-free-sequential-nucleic-acid-and-protein-isolation) *JoVE* is proud to work with these unique scientists and to support DTRA's mission. This partnership poses a unique opportunity for JoVE to help support military services and their allies in an effort to promote counterproliferation, nonproliferation and WMD reduction issues. --- ### Related Posts - [JoVE](https://www.jove.com/) - [Privacy](https://www.jove.com/about/policies)  •   [Terms of Use](https://www.jove.com/about/policies#step-2)  •   [Policies](https://www.jove.com/about/policies) - - [Share on Twitter](http://twitter.com/JoVEjournal) - [Share on Facebook](http://www.facebook.com/JoVEjournal) - [Share on LinkedIn](http://www.linkedin.com/company/jove) - [Contact Us](https://www.jove.com/about/contact) - [Recommend US](https://www.jove.com/recommend-jove-to-your-librarian) - [JoVE NEWSLETTERS](https://www.jove.com/subscribe-to-jove-newsletters) - ###### RESEARCH - [JoVE Journal](https://www.jove.com/journal) - [Methods Collections](https://www.jove.com/methods-collections) - [JoVE Encyclopedia of Experiments](https://www.jove.com/encyclopedia-of-experiments) - 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