...

Reducing Variability in GxP Environments with Scientific Video Content

Ellen Ovenden, MSc & Rucha Joshi, MSc |
Ellen Ovenden, MSc & Rucha Joshi, MSc |

Video-based training is now standard in most research and corporate labs. It’s quick and accessible, but when the videos are not vetted for scientific accuracy, small mistakes can quietly turn into major risks for teams working toward GxP standards and data integrity. Even minor procedural errors can lead to inconsistent results, wasted time, or compliance issues during an audit.

GxP is an umbrella term for the “good practice” quality guidelines that govern regulated research and manufacturing environments. These standards are designed to ensure that every part of a process, from data collection to training, meets a high level of rigor and traceability.

In regulated environments like these, training content must be verified to ensure it reflects accurate, up-to-date scientific practice. Unlike random online videos, platforms featuring scientifically validated content, like JoVE, provide expert-led, high-definition video protocols that reliably represent standard laboratory procedures. 

This validation process makes video training a dependable tool for scientific reproducibility, helping organizations strengthen data integrity, streamline biopharma onboarding, and improve overall lab efficiency.


Defining a Scientifically Validated Platform

“Validation” can mean different things in regulated settings. GxP validation applies to software systems (like LIMS or QMS) that meet 21 CFR Part 11 standards. Scientific validation refers to training content that has been peer-reviewed and verified by experts for accuracy, relevance, and learning value.

1. Accuracy and Reliability ☑️

Validated video content is developed and reviewed by PhD experts to ensure that every demonstrated step reflects current scientific standards. This prevents the errors and inefficiencies that can arise from incomplete or outdated materials.

Non-validated videos often lack such oversight, leaving teams to confirm accuracy themselves. This can introduce inconsistencies, waste valuable time, and increase risk in regulated work.

A reliable lab training platform built on verified content serves as both a scientific training resource and a tool for lab procedure standardization. It provides traceable, citable materials that help organizations maintain high-quality, compliant training across all teams.

2. Reproducibility and Audit Readiness ☑️

Regulators increasingly connect training quality to data integrity. When SOP training is conducted inconsistently, reproducibility declines, and compliance issues can follow.

Scientifically validated, high-definition video protocols remove ambiguity and ensure that all users follow the same approved methods. Such systems maintain version-controlled, reviewable content, creating a transparent record of how staff are trained that supports audit-readiness. 

By using standardized lab protocols that are expert-reviewed and regularly updated, laboratories can increase data quality and maintain alignment between training and practice. Together, these capabilities form the foundation for consistent lab results and support improving lab productivity.

3. Scalability and Global Consistency ☑️

Global R&D and manufacturing teams need training that stays consistent across every site. A video platform built with validated content functions as both a centralized lab knowledge management system and an enterprise video platform for life sciences, helping organizations maintain a unified knowledge base for laboratory training. It delivers standardized, high-quality content on demand and allows teams to track usage and progress worldwide.

With JoVE, tools such as Quiz make it easy to assign videos, monitor completion, assess comprehension, and maintain accurate training records, without repeating in-person sessions. These features help ensure that every scientist, regardless of location, follows the same validated procedures and maintains consistent skills and performance.

  • chrome-capture-2025-10-31
  • chrome-capture-2025-10-31 (2)
  • chrome-capture-2025-10-31 (1)

Real-World Impact: Avastus Preclinical Services

Avastus Preclinical Services, a contract research organization specializing in in vivo studies and complex survival surgeries, faced familiar challenges. New staff needed extensive supervision, training was slow, and critical procedures depended on a few senior scientists. The result: bottlenecks, inconsistent training outcomes, and limited capacity to scale.

To address these issues, Avastus turned to JoVE. Scientists could now access high-quality, on-demand video protocols, previewing every step before entering the lab. Everyone trained with the same accurate, standardized information—reducing training variability and freeing senior staff from repetitive demonstrations to focus on high-value client work.

The impact was immediate and measurable:

  • 💡 Up to 50% faster training time for complex procedures
  • 💡 Improved reproducibility and consistency across experiments
  • 💡 Expanded services and new revenue opportunities from advanced techniques


As CRO Director Connie Larsson, PhD, explained, JoVE turned uncertainty into clarity, helping the team deliver consistent, high-quality work that clients could trust.


Build Training for Quality & Compliance

The right time to modernize lab training is now. A scientifically validated video platform isn’t just efficient; it creates defensible, consistent training records to support audits and is essential for maintaining the goals of  GxP integrity.

Leaders should evaluate their current training methods and consider how high-impact video content can transform not only onboarding and knowledge transfer, but also the way science is executed across teams.

A shift toward validated, reproducible training reflects a long-term commitment to quality and better science. By adopting a validated video platform, labs don’t just improve efficiency and reproducibility; they cultivate a culture of scientific rigor, consistency, and continuous learning.

See how JoVE elevates lab training, reduces rework, and helps you build audit-ready teams.


Related Posts